Rhabdomyolysis due to an uncommon interaction of ciprofloxacin with simvastatin.
نویسنده
چکیده
A case report of a ciprofloxacin and simvastatin interaction is presented. The addition of ciprofloxacin to chronic simvastatin therapy led to the development of rhabdomyolysis. As ciprofloxacin is a weak inhibitor of CYP3A4, it is very likely that other mechanisms involving the ATP-binding cassette drug efflux transporter family played a role in this drug interaction.
منابع مشابه
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عنوان ژورنال:
- The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique
دوره 16 1 شماره
صفحات -
تاریخ انتشار 2009